Dale Miles Selected Research

sapphyrin

1/2007	Synthesis and biologic properties of hydrophilic sapphyrins, a new class of tumor-selective inhibitors of gene expression.
11/2006	Tumor localization and antitumor efficacy of novel sapphyrin compounds.

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Dale Miles Research Topics

Disease

11	Neoplasms (Cancer) 01/2018 - 05/2005
6	B-Cell Chronic Lymphocytic Leukemia (Chronic Lymphocytic Leukemia) 01/2022 - 12/2019
5	Non-Hodgkin Lymphoma (Lymphosarcoma) 01/2022 - 01/2020
3	Neutropenia 04/2022 - 01/2020
3	Infections 04/2022 - 01/2020
2	Acute Myeloid Leukemia (Acute Myelogenous Leukemia) 04/2022 - 01/2021
2	Thrombocytopenia (Thrombopenia) 04/2022 - 01/2022
2	Residual Neoplasm 12/2021 - 01/2021
2	Hematologic Neoplasms (Hematological Malignancy) 01/2021 - 01/2007
2	Chromosome Aberrations (Chromosome Abnormalities) 01/2020 - 12/2019
2	Fatigue 01/2018 - 01/2018
2	Thyroid Neoplasms (Thyroid Cancer) 01/2018 - 01/2016
2	Renal Cell Carcinoma (Grawitz Tumor) 01/2018 - 01/2018
2	Diarrhea 01/2018 - 01/2018
2	medullary Thyroid cancer 01/2016 - 09/2015
1	Lymphoma (Lymphomas) 01/2022
1	Body Weight (Weight, Body) 11/2021
1	Invasive Fungal Infections 01/2021
1	Diffuse Large B-Cell Lymphoma (Lymphoma, Large Cell, Diffuse) 12/2020
1	Lymphoid Leukemia 01/2020
1	Hepatic Insufficiency 01/2019
1	Asthenia 01/2018
1	Hypertension (High Blood Pressure) 01/2018
1	Nausea 01/2018
1	Glioblastoma (Glioblastoma Multiforme) 01/2018
1	Prostatic Neoplasms (Prostate Cancer) 01/2018
1	Exanthema (Rash) 01/2018
1	Disease Progression 01/2018
1	Carcinoma (Carcinomatosis) 09/2005
1	Lung Neoplasms (Lung Cancer) 05/2005

Drug/Important Bio-Agent (IBA)

9	venetoclaxIBA 04/2022 - 01/2019
5	Rituximab (Mabthera)FDA Link 01/2022 - 12/2019
5	polatuzumab vedotinIBA 12/2020 - 01/2020
5	Tyrosine Kinase InhibitorsIBA 01/2018 - 09/2015
4	cabozantinibIBA 01/2018 - 09/2015
3	obinutuzumabIBA 01/2022 - 01/2020
3	Antineoplastic Agents (Antineoplastics)IBA 01/2021 - 11/2006
3	Pharmaceutical PreparationsIBA 01/2018 - 05/2005
2	Prednisone (Sone)FDA LinkGeneric 01/2022 - 01/2020
2	Doxorubicin (Adriamycin)FDA LinkGeneric 01/2022 - 01/2020
2	Cyclophosphamide (Cytoxan)FDA LinkGeneric 01/2022 - 01/2020
2	Cytochrome P-450 CYP3AIBA 01/2021 - 09/2015
2	Immunoconjugates (Immunoconjugate)IBA 01/2020 - 01/2020
2	GSK 1363089IBA 12/2015 - 06/2013
2	Phosphotransferases (Kinase)IBA 12/2015 - 06/2013
2	sapphyrinIBA 01/2007 - 11/2006
2	PCI 2050IBA 01/2007 - 11/2006
2	motexafin gadoliniumIBA 09/2005 - 05/2005
1	Cytarabine (Cytosar-U)FDA LinkGeneric 04/2022
1	Vincristine (Oncovin)FDA LinkGeneric 01/2022
1	Proteins (Proteins, Gene)FDA Link 01/2022
1	EnzymesIBA 01/2021
1	Cytochrome P-450 Enzyme System (Cytochrome P450)IBA 01/2021
1	posaconazole FDA Link 01/2021
1	Bendamustine Hydrochloride FDA Link 12/2020
1	monomethyl auristatin EIBA 01/2020
1	Everolimus FDA Link 01/2018
1	XL647IBA 01/2018
1	TabletsIBA 01/2018
1	Cytochrome P-450 CYP3A InhibitorsIBA 09/2015
1	Ketoconazole (Nizoral)FDA LinkGeneric 09/2015
1	Rosiglitazone (Avandia)FDA Link 09/2015
1	Cytochrome P-450 CYP2C8IBA 09/2015
1	Rifampin (Rifampicin)FDA LinkGeneric 09/2015
1	Phosphatidylinositols (Phosphatidylinositol)IBA 05/2014
1	XL765IBA 05/2014
1	Mechanistic Target of Rapamycin Complex 1IBA 05/2014
1	Mechanistic Target of Rapamycin Complex 2IBA 05/2014
1	PorphyrinsIBA 01/2007
1	Biological ProductsIBA 01/2007
1	PCI 2000IBA 11/2006
1	Folic Acid AntagonistsIBA 09/2005
1	EstersIBA 09/2005
1	Methotrexate (Mexate)FDA LinkGeneric 09/2005
1	Glutamic Acid (Glutamate)FDA Link 09/2005
1	CationsIBA 05/2005
1	MetalsIBA 05/2005
1	ZincIBA 05/2005

Therapy/Procedure

4	Therapeutics 01/2021 - 01/2018
1	Drug Therapy (Chemotherapy) 04/2022
1	Duration of Therapy 11/2021
1	Castration 01/2018